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紅景天為景天科天屬Rhodiola L.的多年生草本或葉灌木，常具肉質根及根狀莖，是近年新開發的新興中草藥，主要以其根和根莖入藥，全株亦可入藥。性涼，味甘、苦、澀，有養肺清熱、滋補元氣的功能。製劑能增強體力和抵抗力，因此通常用作對慢性病和體弱易感染病人的治療。臨床用於治療神經衰落弱和神經官能症，提高注意力、記憶力，高原紅細胞增多症，高血壓病；作為興奮神經劑，用於提高智能力、改善植物神經-血管張力障礙有肌無力等；用於自由基增多的疾患，如腫瘤，幅射損傷，肺氣腫，老年白內障等；還作為強壯劑，用於陽 痿等；紅景天製劑還用於運動醫學及航天醫學，用於在各種特殊環境條件下工作人員的健康防護。具有滋補強壯、抗缺氧、抗微波幅射、抗毒、活血化瘀、抗腫瘤、抗衰老等作用，同時對神經系統、內分泌系統、心肌缺氧耐力、物質代謝等均有良好的影響與作用。
國內外的歷史考證 根據史料記載，我國古代人民從公元八世紀起就有用紅景天治療疾病的記載，【四部醫典】記："蘇洛瑪保"有治血病、赤巴病、瘡療潰爛。【溫島合】記："蘇洛瑪保"清熱養肺，補元氣，除口臭，浸水沐浴消除諸病，亦作供神的祭品。相繼在【甘露之滴】、【圖鑑】、【晶珠本草】中均記載有清肺熱、除疫癘、治脈病、肺病、瘟病時疫等。又據記載，清朝歷代皇帝專門派員尋找紅景天，並向各地索取紅景天作為貢品。康熙在西北地區平息動亂的征戰中因人蔘熱量過盛而選用紅景天作為清除軍旅疲勞，提高戰鬥力的藥物。據國外藥典記載，早就在民間醫學中用來治療疾病。前蘇聯現代勃列克赫曼學派對人蔘、刺五加、紅景天等進行了深入研究，提出了相似我國中醫"扶正固本"的"適應原"學說，認定紅景天植物有良好的"適應原"樣的作用，具免疫作用優於人蔘。據此學說，薩拉季科夫教授從紅景天（Rhodiola rosea L.）中分離出具有滋補強壯作用的紅景天苷（Salidroside）和酪醇（Tgrodsol），並從中發現紅景天根及根莖中含有多達十幾種具有生物活性的微量元素。他認為不能用自然方法克服過度疲勞而恢復精力時，服用紅景天流浸膏有顯著效果且無毒無成癮性，還能用紅景天製造不含酒精但能增強類似酒類快感，並能提高工作效率的飲料。前蘇聯還通過數理統計方法選出最優紅景天在流浸膏的配方比例，製成紅景天製劑。如景天浸膏片，給予航員、飛行員、潛水員、運動員和從事勞動強度大的人服用。蘇科學家還發現紅景天苷及其苷元對老年性心肌衰弱、陽痿、糖尿病、肺結核、神經衰弱等均有顯著治療作用。
紅景天屬植物在全球約有近100種，我國有70餘種，青康藏高原有55種，西藏有32種，分佈於我國東北、華北、西北及西南的高寒山區。野生資源極少。西藏是素有"世界屋脊"著稱的青藏高原的主體部份，由於它特有的自然地理、氣候條件，造就了一大群特有的植物種群，不只在形態上，生理上特殊，其內含活性成份亦複雜而量多。這些種群大都分佈在海拔3000-5000 m的高原地帶。紅景天便是這個類群的代表之一。現已知本屬植物含紅景天苷的有有14種。目前作藥用或保健品應用的種類有：大花紅景天Rhodiola crenulata(
Hook.f.et Thomx.)H.Ohba，紅景天R. Rosea L，庫頁紅景天R. sachalinensis A.Bor.，狹葉紅景天R. kirilowii(Regel)Maxim.，深紅紅景天R.coccinea(Royle)A.Bor.。
大花紅景天主要成份為：紅景天苷（Salidroside）及其苷元酪醇（Tryosol）、6-氧-沒食子醯基紅景天苷、1,2,3,4,6-五氧-沒食子醯基-β-D-呲喃葡萄糖、草質素-7-氧-α-L-呲喃李糖苷、草質素-7-氧-（3-氧-β-D-呲喃葡萄糖基）-α-L-呲喃李糖苷；另外還含有黃酮苷、沒食子酸、山奈酚、槲皮素、酪薩維(Rosavin)、酪生(Rosarin)、酪薩利(Rosin)等結構等。紅景天根中含有黃酮苷Rhodionin、Rhodiosin、Rhodiolin，約有30種揮發油，其中Sosaol含量最高，占約26%，還有β-石竹烯、α-橄香烯等。地上部份含有Rhodiolgin、Rhodionidin和Rhodiolgidin等。紅景天不同種的植物中紅景天苷的含量相差較大，經由HPLC等不同的方法測定10種紅景天植物中的紅景天苷和百脈苷含量，其中以狹葉紅景天、吉氏紅景天、四裂紅景天、對葉紅景天，所含紅景天苷和百脈苷為高含量。
紅景天功用
認識紅景天 紅景天功用 參考文獻
1 .抗疲勞作用 口服狹葉紅景天使小鼠爬欄時間、游泳時間和負荷游泳時間延長。能縮短疲勞之後恢復所需時間，提高酶、 RNA和蛋白質水平，使疲勞後肌肉儘快恢復（3, 23, 71）。
2 .對中樞神經介質的影響 紅景天能使小鼠在游泳條件下5-羥色胺含量正常化，即已離正常沙丘中樞神經介質含量得到糾正或達到正常水平。小鼠注射紅景天苷(30-300mg/kg)能降低5-羥色胺的水平（15,23）。
在有憂鬱症大白鼠的實驗中，紅景天可以改善受傷大腦的海馬迴中的血清素濃度回復到正常，並刺激幹細胞修復神經原（61, 65）。在大腦缺血時，紅景天苷可以保護神經元細胞，降低其傷害(72)。可以保護神經細胞，降低自由基的傷害(78)。
3 .抗缺氧作用 口服紅景天、狹葉紅景天、深紅紅景天的提取物均可使試驗動物對各種缺氧模式表現出明顯對抗作用，其作用強於人蔘和刺五加，且增加心臟冠狀動脈的血流量，並降低心臟病的發生率（5,21,23,34,37,38）。可以保護心肌細胞，減少缺氧對心肌細胞細胞凋亡及壞死(67)。紅景天萃取物可以抑制母鼠的行為和生理在慢性壓力下的改變(69)。
4 . 抗衰老作用 大紅紅景天醇提取物能提高大白鼠紅細胞、肝臟SOD的活性，並有增加心肌SOD活性的趨勢。紅野亞麻蠅飲用紅景天提取液，可明顯延長壽命，延壽率優於人蔘。紅景天素有促進2BS細胞增殖和降低死亡率的作用，能抑制大鼠細胞過氧化脂質和增強血清超氧化物歧化酶的活性（5,22,23,24,34,54）。 是不錯的細胞保護劑和抗氧化劑 (55)。 根據體外試驗，紅景天抗自由基的能力，其能力並非為主要的抗自由基主力，相反的無明確證據顯示具有強力的抗自由基功能( 59, 60 ) 。 Salidroside可以保護內皮細胞因氯化鈷所誘導的細胞凋亡(63)。
5 .抗腫瘤 紅景天素對S180細胞確有一定的抑制作用，在無毒副劑量範圍內，這種作用隨濃度增大而增強。連續口服紅景天提取物可降低變紅菌素對小鼠小腸璧的致癌損傷程度，並提高機體抗癌能力（23,26,33,36,41,42,43,45）。可以抑制血癌中的白血球生長，是個潛在有效的細胞抑制劑 (49, 76)。大花紅景天可以抑制乳癌細胞的生長和誘導其死亡(73)。
6 .解毒作用 紅景天具有拮抗士的寧中毒作用，能提高士的寧中毒後小鼠的生存率達50%；還具有拮抗棒狀桿菌毒素的作用，並能對抗破傷風等各種細菌毒素，增加服用烈性毒藥、氰化納、亞硝酸鈉小鼠存活時間或生存率（11,12,13,23）。紅景天苷可以保護小白鼠因乙醯胺酚的肝毒性對肝臟的傷害(74)。
7 .其他作用 紅景天有適應原樣作用和雙向調節作用。經微波幅射的小鼠腦內單胺递質、脾臟及胸腺內環磷酸腺苷、淋巴細胞轉化率、血清溶血素等出現抑制性變化，紅景天可使之恢復正常。注射紅景天苷後，能增強家兔的甲狀腺功能及腎上腺功能，並能興奮小鼠卵內分泌功能。提高注意力和記憶力。提高血槳中β-吲哚酚的水平，阻止壓力激素的變化（7,10,27,28,29,31,32,35,39,44）。 提高人體T淋巴球免疫能力(66)。
8 .對肝臟具有保護的作用（8,19,40）。
9 .可以降低流行性感冒病毒(H1N1, H9N2)活性的作用(58)。紅景天苷具有抗腸病毒 克沙奇B3型 (Coxsackievirus B3) 病毒的能力(70)。
10 . 紅景天中的活性成份Salidroside，可以抑制在高血糖情況下誘導腎小球膜細胞增生(62)。在大白鼠的實驗中，紅景天萃取物可以降低大白鼠糖尿病發生率(64)。紅景天苷可以提升肌肉細胞對胰島素的感受度，減少糖尿病的發生(75)。
11 .紅景天的根可以抑制單胺氧化酶的活性，降低憂鬱症的發生(68)。
12 .可以緩解壓力，降低厭食症發生的機率(77)。
參考文獻
認識紅景天 紅景天功用 參考文獻
1.Akgul Y, Ferreira D, Abourashed EA, Khan IA.(2004) Lotaustralin from Rhodiola rosea roots. Fitoterapia. 2004 Sep;75(6):612-4.
2.Tolonen A, Gyorgy Z, Jalonen J, Neubauer P, Hohtola A. (2004) LC/MS/MS identi fi cation of glycosides produced by biotransformation of cinnamyl alcohol in Rhodiola rosea compact callus aggregates. Biomed Chromatogr. 2004 Oct;18(8):550.
3.De Bock K, Eijnde BO, Ramaekers M, Hespel P.(2004) Acute Rhodiola rosea intake can improve endurance exercise performance. Int J Sport Nutr Exerc Metab. 2004 Jun;14(3):298-307.
4.Kucinskaite A, Briedis V, Savickas A.(2004) [Experimental analysis of therapeutic properties of Rhodiola rosea L. and its possible application in medicine] Medicina (Kaunas). 2004;40(7):614-9.
5.Wing SL, Askew EW, Luetkemeier MJ, Ryujin DT, Kamimori GH, Grissom CK.(2004) Lack of effect of Rhodiola or oxygenated water supplementation on hypoxemia and oxidative stress. Wilderness Environ Med. 2003 Spring;14(1):9-16.
6.Cui S, Hu X, Chen X, Hu Z(2003) Determination of p-tyrosol and salidroside in three samples of Rhodiola crenulata and one of Rhodiola kirilowii by capillary zone electrophoresis. Anal Bioanal Chem. 2003 Sep;377(2):370-4. Epub 2003 Jul 19.
7.Zhu BW, Sun YM, Yun X, Han S, Piao ML, Murata Y, Tada M.(2003) Reduction of noise-stress-induced physiological damage by radices of Astragali and Rhodiolae: glycogen, lactic acid and cholesterol contents in liver of the rat. Biosci Biotechnol Biochem. 2003 Sep;67(9):1930-6.
8.Song EK, Kim JH, Kim JS, Cho H, Nan JX, Sohn DH, Ko GI, Oh H, Kim YC.(2003) Hepatoprotective phenolic constituents of Rhodiola sachalinensis on tacrine-induced cytotoxicity in Hep G2 cells. Phytother Res. 2003 May;17(5):563-5.
9.Lei Y, Nan P, Tsering T, Bai Z, Tian C, Zhong Y.(2003) Chemical composition of the essential oils of two Rhodiola species from Tibet. Z Naturforsch [C]. 2003 Mar-Apr;58(3-4):161-4.
10.Shevtsov VA, Zholus BI, Shervarly VI, Vol'skij VB, Korovin YP, Khristich MP, Roslyakova NA, Wikman G.(2003) A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine. 2003 Mar;10(2-3):95-105.
11.Pashkevich IA, Uspenskaia IuA, Nefedova VV, Egorova AB.(2003) Comparative evaluation of effects of p-tyrosol and Rhodiola rosea extract on bone marrow cells in vivo Eksp Klin Farmakol. 2003 Jul-Aug;66(4):50-2.
12.Wu XL, Zeng WZ, Wang PL, Lei CT, Jiang MD, Chen XB, Zhang Y, Xu H, Wang Z.(2003) Effect of compound rhodiola sachalinensis A Bor on CCl4-induced liver fibrosis in rats and its probable molecular mechanisms. World J Gastroenterol. 2003 Jul;9(7):1559-62.
13.Nan JX, Jiang YZ, Park EJ, Ko G, Kim YC, Sohn DH.(2003) Protective effect of Rhodiola sachalinensis extract on carbon tetrachloride-induced liver injury in rats. J Ethnopharmacol. 2003 Feb;84(2-3):143-8.
14.Wu S, Zu Y, Wu M.(2003) High yield production of salidroside in the suspension culture of Rhodiola sachalinensis. J Biotechnol. 2003 Dec 5;106(1):33-43.
15.Provalova NV, Skurikhin EG, Pershina OV, Minakova MY, Suslov NI, Dygai AM.(2003) Possible mechanisms underlying the effect of natural preparations on erythropoiesis under conditions of conflict situation. Bull Exp Biol Med. 2003 Aug;136(2):165-9.
16.Tolonen A, Hohtola A, Jalonen J.(2003) Comparison of electrospray ionization and atmospheric pressure chemical ionization techniques in the analysis of the main constituents from Rhodiola rosea extracts by liquid chromatography/mass spectrometry. J Mass Spectrom. 2003 Aug;38(8):845-53
17.Tolonen A, Pakonen M, Hohtola A, Jalonen J.(2003) Phenylpropanoid glycosides from Rhodiola rosea. Chem Pharm Bull (Tokyo). 2003 Apr;51(4):467-70.
18.Han X, Zhang T, Wei Y, Cao X, Ito Y.(2003) Separation of salidroside from Rhodiola crenulata by high-speed counter-current chromatography. J Chromatogr A. 2002 Sep 20;971(1-2):237-41.
19.Iaremii IN, Grigor'eva NF.(2002) Hepatoprotective properties of liquid extract of Rhodiola rosea Eksp Klin Farmakol. 2002 Nov-Dec;65(6):57-9.
20.Rohloff J.(2002) Volatiles from rhizomes of Rhodiola rosea L. Phytochemistry. 2002 Mar;59(6):655-61.
21.Pogorelyi VE, Makarova LM.(2002) Rhodiola rosea extract for prophylaxis of ischemic cerebral circulation disorder Eksp Klin Farmakol. 2002 Jul-Aug;65(4):19-22.
22.Mook-Jung I, Kim H, Fan W, Tezuka Y, Kadota S, Nishijo H, Jung MW.(2002) Neuroprotective effects of constituents of the oriental crude drugs, Rhodiola sacra, R. sachalinensis and Tokaku-joki-to, against beta-amyloid toxicity, oxidative stress and apoptosis. Biol Pharm Bull. 2002 Aug;25(8):1101-4.
23.Kelly GS.(2001) Rhodiola rosea: a possible plant adaptogen. Altern Med Rev. 2001 Jun;6(3):293-302.
24.Ip SP, Che CT, Leung PS.(2001) Association of free radicals and the tissue renin-angiotensin system: prospective effects of Rhodiola, a genus of Chinese herb, on hypoxia-induced pancreatic injury. JOP. 2001 Jan;2(1):16-25.
25.Ganzera M, Yayla Y, Khan IA.(2001) Analysis of the marker compounds of Rhodiola rosea L. (golden root) by reversed phase high performance liquid chromatography. Chem Pharm Bull (Tokyo). 2001 Apr;49(4):465-7.
26.Razina TG, Zueva EP, Amosova EN, Krylova SG.(2000) Medicinal plant preparations used as adjuvant therapeutics in experimental oncology Eksp Klin Farmakol. 2000 Sep-Oct;63(5):59-61.
27.Boon-Niermeijer EK, van den Berg A, Wikman G, Wiegant FA.(2000) Phyto-adaptogens protect against environmental stress-induced death of embryos from the freshwater snail Lymnaea stagnalis. Phytomedicine. 2000 Oct;7(5):389-99.
28.Darbinyan V, Kteyan A, Panossian A, Gabrielian E, Wikman G, Wagner H.(2000) Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine. 2000 Oct;7(5):365-71.
29.Spasov AA, Mandrikov VB, Mironova IA.(2000) The effect of the preparation rodakson on the psychophysiological and physical adaptation of students to an academic load Eksp Klin Farmakol. 2000 Jan-Feb;63(1):76-8.
30.Linh PT, Kim YH, Hong SP, Jian JJ, Kang JS.(2000) Quantitative determination of salidroside and tyrosol from the underground part of Rhodiola rosea by high performance liquid chromatography. Arch Pharm Res. 2000 Aug;23(4):349-52.
31.Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV.(2000) A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine. 2000 Apr;7(2):85-9.
32.Maimeskulova LA, Maslov LN.(1998) The anti-arrhythmia action of an extract of Rhodiola rosea and of n-tyrosol in models of experimental arrhythmias Eksp Klin Farmakol. 1998 Mar-Apr;61(2):37-40.
33.Salikhova RA, Aleksandrova IV, Mazurik VK, Mikhailov VF, Ushenkova LN, Poroshenko GG.(1997) Effect of Rhodiola rosea on the yield of mutation alterations and DNA repair in bone marrow cells Patol Fiziol Eksp Ter. 1997 Oct-Dec(4):22-4.
34.Lishmanov IuB, Naumova AV, Afanas'ev SA, Maslov LN.(1997) Contribution of the opioid system to realization of inotropic effects of Rhodiola rosea extracts in ischemic and reperfusion heart damage in vitro Eksp Klin Farmakol. 1997 May-Jun;60(3):34-6.
35.Maimeskulova LA, Maslov LN, Lishmanov IuB, Krasnov EA.(1997) The participation of the mu-, delta- and kappa-opioid receptors in the realization of the anti-arrhythmia effect of Rhodiola rosea Eksp Klin Farmakol. 1997 Jan-Feb;60(1):38-9.
36.Bocharova OA, Matveev BP, Baryshnikov AIu, Figurin KM, Serebriakova RV, Bodrova NB.(1995) The effect of a Rhodiola rosea extract on the incidence of recurrences of a superficial bladder cancer (experimental clinical research) Urol Nefrol (Mosk). 1995 Mar-Apr(2):46-7.
37.Maslova LV, Kondrat'ev BIu, Maslov LN, Lishmanov IuB.(1994) The cardioprotective and antiadrenergic activity of an extract of Rhodiola rosea in stress Eksp Klin Farmakol. 1994 Nov-Dec;57(6):61-3.
38.Afanas'ev SA, Alekseeva ED, Bardamova IB, Maslova LV, Lishmanov IuB.(1993) Afanas'ev SA, Alekseeva ED, Bardamova IB, Maslova LV, Lishmanov IuB. Biull Eksp Biol Med. 1993 Nov;116(11):480-3.
39.Lishmanov IuB, Maslova LV, Maslov LN, Dan'shina EN.(1993) The anti-arrhythmia effect of Rhodiola rosea and its possible mechanism Biull Eksp Biol Med. 1993 Aug;116(8):175-6.
40.Udintsev SN, Krylova SG, Fomina TI.(1992) The enhancement of the efficacy of adriamycin by using hepatoprotectors of plant origin in metastases of Ehrlich's adenocarcinoma to the liver in mice Vopr Onkol. 1992;38(10):1217-22.
41.Udintsev SN, Shakhov VP, Borovskoi IG.(1991) Mechanism of differential effect of low dose adaptogens on the functional activity of normal and transformed cellular elements in vitro Biofizika. 1991 Jul-Aug;36(4):624-7.
42.Udintsev SN, Shakhov VP.(1990) Changes in clonogenic properties of bone marrow and transplantable mice tumor cells during combined use of cyclophosphane and biological response modifiers of adaptogenic origin Eksp Onkol. 1990;12(6):55-6.
43.Udintsev SN, Shakhov VP.(1989) Decrease in the growth rate of Ehrlich's tumor and Pliss' lymphosarcoma with partial hepatectomy Vopr Onkol. 1989;35(9):1072-5.
44.Lishmanov IuB, Trifonova ZhV, Tsibin AN, Maslova LV, Dement'eva LA.(1987) Plasma beta-endorphin and stress hormones in stress and adaptation Biull Eksp Biol Med. 1987 Apr;103(4):422-4.
45.Dement'eva LA, Iaremenko KV.(1987) Effect of a Rhodiola extract on the tumor process in an experiment Vopr Onkol. 1987;33(7):57-60.
46.Petkov VD, Yonkov D, Mosharoff A, Kambourova T, Alova L, Petkov VV, Todorov I.(1986) Effects of alcohol aqueous extract from Rhodiola rosea L. roots on learning and memory. Acta Physiol Pharmacol Bulg. 1986;12(1):3-16.
47.徐良，中國 GAP 藥材與中藥現代化開發指南：中國名貴藥材規範化栽培與產業化開發新技術（ 2001 ），中華人民共和國協和醫科大學出版社。 (Simple Chinese)
48.江蘇新醫學院，中藥大辭典（ 1999 ），上海科學技術出版社。 (Simple Chinese)
49 . Majewska A, Hoser G, Furmanowa M, Urbanska N, Pietrosiuk A, Zobel A, Kuras M.(2006) Antiproliferative and antimitotic effect, S phase accumulation and induction of apoptosis and necrosis after treatment of extract from Rhodiola rosea rhizomes on HL-60 cells.J Ethnopharmacol. 2006 Jan 3;103(1):43-52.
50 .Yousef GG, Grace MH, Cheng DM, Belolipov IV, Raskin I, Lila MA.(2006) Comparative phytochemical characterization of three Rhodiola species.Phytochemistry. 2006 Sep 4
51 . Ma G, Li W, Dou D, Chang X, Bai H, Satou T, Li J, Sun D, Kang T, Nikaido T, Koike K.(2006) Rhodiolosides A-E, monoterpene glycosides from Rhodiola rosea.Chem Pharm Bull (Tokyo). 2006 Aug;54(8):1229-33.
52 . Petsalo A, Jalonen J, Tolonen A.(2006) Identification of flavonoids of Rhodiola rosea by liquid chromatography-tandem mass spectrometry.J Chromatogr A. 2006 Apr 21;1112(1-2):224-31.
53 .Ming DS, Hillhouse BJ, Guns ES, Eberding A, Xie S, Vimalanathan S, Towers GH.(2005) Bioactive compounds from Rhodiola rosea (Crassulaceae).Phytother Res. 2005 Sep;19(9):740-3.
54 .Battistelli M, De Sanctis R, De Bellis R, Cucchiarini L, Dacha M, Gobbi P.(2005) Rhodiola rosea as antioxidant in red blood cells: ultrastructural and hemolytic behaviour.Eur J Histochem. 2005 Jul-Sep;49(3):243-54.
55 .Kanupriya, Prasad D, Sai Ram M, Kumar R, Sawhney RC, Sharma SK, Ilavazhagan G, Kumar D, Banerjee PK.(2005) Cytoprotective and antioxidant activity of Rhodiola imbricata against tert-butyl hydroperoxide induced oxidative injury in U-937 human macrophages.Mol Cell Biochem. 2005 Jul;275(1-2):1-6
56 .Wang Q, Ruan X, Jin ZH, Yan QC, Tu S.(2005) Identification of Rhodiola species by using RP-HPLC.J Zhejiang Univ Sci B. 2005 Jun;6(6):477-82.
57 .Tolonen A, Gyorgy Z, Jalonen J, Neubauer P, Hohtola A.(2004) LC/MS/MS identification of glycosides produced by biotransformation of cinnamyl alcohol in Rhodiola rosea compact callus aggregates.Biomed Chromatogr. 2004 Oct;18(8):550-8.
58 .Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.(2009) Jeong HJ, Ryu YB, Park SJ, Kim JH, Kwon HJ, Kim JH, Park KH, Rho MC, Lee WS.Bioorg Med Chem. 2009 Oct 1;17(19):6816-23.
59 .Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses.(2009)Schriner SE, Avanesian A, Liu Y, Luesch H, Jafari M.Free Radic Biol Med. 2009 Sep 1;47(5):577-84. Epub 2009 May 29.
60 .Decreased mitochondrial superoxide levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rosea.(2009)Schriner SE, Abrahamyan A, Avanessian A, Bussel I, Maler S, Gazarian M, Holmbeck MA, Jafari M.Free Radic Res. 2009 Sep;43(9):836-43.
61 .The effects of Rhodiola rosea extract on 5-HT level, cell proliferation and quantity of neurons at cerebral hippocampus of depressive rats.(2009)Chen QG, Zeng YS, Qu ZQ, Tang JY, Qin YJ, Chung P, Wong R, Hägg U.Phytomedicine. 2009 Sep;16(9):830-8.
62 .Salidroside, the main active compound of Rhodiola plants, inhibits high glucose-induced mesangial cell proliferation.(2009)Yin D, Yao W, Chen S, Hu R, Gao X.Planta Med. 2009 Sep;75(11):1191-5.
63 .Protective effects of salidroside on endothelial cell apoptosis induced by cobalt chloride.(2009)Tan CB, Gao M, Xu WR, Yang XY, Zhu XM, Du GH.Biol Pharm Bull. 2009 Aug;32(8):1359-63.
64 .Antidiabetic potential of Rhodiola sachalinensis root extract in streptozotocin-induced diabetic rats.(2009)Gao D, Li Q, Liu Z, Feng J, Li J, Han Z, Duan Y.Methods Find Exp Clin Pharmacol. 2009 Jul-Aug;31(6):375-81.
65 .Protective effect of salidroside against H(2)O (2)-induced cell apoptosis in primary culture of rat hippocampal neurons.(2009)Chen X, Zhang Q, Cheng Q, Ding F.Mol Cell Biochem. 2009 Jun 25.
66 .Production of Th1- and Th2-dependent cytokines induced by the Chinese medicine herb, Rhodiola algida, on human peripheral blood monocytes.(2009)Li HX, Sze SC, Tong Y, Ng TB. Ethnopharmacol. 2009 Jun 22;123(2):257-66.
67 .Salidroside protects cardiomyocyte against hypoxia-induced death: a HIF-1alpha-activated and VEGF-mediated pathway.(2009)Zhang J, Liu A, Hou R, Zhang J, Jia X, Jiang W, Chen J.Eur J Pharmacol. 2009 Apr 1;607(1-3):6-14.
68 .Monoamine oxidase inhibition by Rhodiola rosea L. roots.(2009)van Diermen D, Marston A, Bravo J, Reist M, Carrupt PA, Hostettmann K.J Ethnopharmacol. 2009 Mar 18;122(2):397-401.
69 .Effects of Rhodiola rosea L. extract on behavioural and physiological alterations induced by chronic mild stress in female rats.(2009)Mattioli L, Funari C, Perfumi M.J Psychopharmacol. 2009 Mar;23(2):130-42. Epub 2008 May 30.
70 .The in vitro and in vivo antiviral effects of salidroside from Rhodiola rosea L. against coxsackievirus B3.(2009)Wang H, Ding Y, Zhou J, Sun X, Wang S.Phytomedicine. 2009 Mar;16(2-3):146-55.
71 .Chronic Rhodiola rosea extract supplementation enforces exhaustive swimming tolerance.(2009)Lee FT, Kuo TY, Liou SY, Chien CT.Am J Chin Med. 2009;37(3):557-72.
72 .Neuroprotective effects of salidroside in the PC12 cell model exposed to hypoglycemia and serum limitation.(2008)Yu S, Liu M, Gu X, Ding F.Cell Mol Neurobiol. 2008 Dec;28(8):1067-78.
73 .Rhodiola crenulata induces death and inhibits growth of breast cancer cell lines.(2008)Tu Y, Roberts L, Shetty K, Schneider SS.J Med Food. 2008 Sep;11(3):413-23.
74 .Protective effects of salidroside against cetaminophen-induced toxicity in mice.(2008)Wu YL, Piao DM, Han XH, Nan JX.Biol Pharm Bull. 2008 Aug;31(8):1523-9.
75 .Salidroside stimulated glucose uptake in skeletal muscle cells by activating AMP-activated protein kinase.Li HB, Ge YK, Zheng XX, Zhang L.Eur J Pharmacol. 2008 Jul 7;588(2-3):165-9.
76 .Aqueous extract of Rhodiola imbricata rhizome inhibits proliferation of an erythroleukemic cell line K-562 by inducing apoptosis and cell cycle arrest at G2/M phase.(2008)Mishra KP, Padwad YS, Dutta A, Ganju L, Sairam M, Banerjee PK, Sawhney RC.Immunobiology. 2008;213(2):125-31..
77 .Rhodiola rosea L. extract reduces stress- and CRF-induced anorexia in rats.(2007)Mattioli L, Perfumi M.J Psychopharmacol. 2007 Sep;21(7):742-50.
78 .Protective effects of salidroside on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells.(2007)Zhang L, Yu H, Sun Y, Lin X, Chen B, Tan C, Cao G, Wang Z.Eur J Pharmacol. 2007 Jun 14;564(1-3):18-25.
